Prof. J. Stanley Gardiner, F.R.S

Stanley J. Korsmeyer

The scientific community has been saddened and diminished by the loss of Stanley J. Korsmeyer, M.D., who died of lung cancer last month at the age of 54. Over the last 25 years, Korsmeyer had been an international leader in the fields of cancer biology and programmed cell death (apoptosis). Through his studies of apoptosis, Korsmeyer helped revolutionize our concepts of carcinogenesis. Korsmeye...

By Stanley J . Korsmeyer , Philip a . Hieter ,

The maturation of a pre-B cell to an immunoglobulin (Ig)-bearing B cell requires an effective recombination of a light chain variable (VL) 1 and joining (JL) gene segment (1-11). Man uses both light chain gene classes appreciably, expressing K light chain in -60% and ~ light chain in 40% of mature B cells. Despite their nearly equal usage, however, the rearrangement of human Ig light chain gene...

Prof. Dr. Prof. Prof.

Reply to J M Stanley: fiddling and clarity.

The author responds to John M. Stanley's criticism ("More fiddling with the definition of death?" Journal of Medical Ethics 1987 Mar; 13(1): 21-22) and clarifies the arguments in his own previous article ("Why let people die?" Journal of Medical Ethics 1986 Jun; 12(2): 83-86). Gillett contends that we must decide what ethical stance we should adopt toward the living but nonsentient, devoid of ...

Dr. Robert Gardiner Hill